Combination chemotherapy is also the treatment of choice for disease that is extensive or cannot be removed surgically. Radiation therapy is often also used to eliminate any potential residual tumor cells , often in conjunction with chemotherapy.
    Recent reports associate the infection Helicobacter pylori with small bowel lymphomas. Eradication of the bacteria with antibiotics may lead to a regression of lymphomas in some cases.

               Palliation  Radiation therapy can relieve the symptoms associated with large lymphomas that cannot
               be removed, often in combination with chemotherapy. Single liver metastases may respond well to radiation (survival chances decrease as the number of metastases increases).

Five-Year Survival  25 percent for diffuse lymphoma, 50 percent or more for nodular lymphoma

Investigational 
• Adjuvant radiotherapy and chemotherapy are being studied.